Incorporating gene functions as priors in model-based clustering of microarray gene expression data

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Incorporating gene functions as priors in model-based clustering of microarray gene expression data

MOTIVATION Cluster analysis of gene expression profiles has been widely applied to clustering genes for gene function discovery. Many approaches have been proposed. The rationale is that the genes with the same biological function or involved in the same biological process are more likely to co-express, hence they are more likely to form a cluster with similar gene expression patterns. However,...

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ژورنال

عنوان ژورنال: Bioinformatics

سال: 2006

ISSN: 1367-4803,1460-2059

DOI: 10.1093/bioinformatics/btl011